Diabetes Diet for Patients with Kidney Disease

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Diabetes is a major cause of various serious kidney diseases. It is estimated that more than 35 percent of diabetes are affected by serious diseases of the kidneys. The advancement of kidney disease is very fast in diabetics. This is especially true when there is poor control on diabetes. Proper diet for diabetics with kidney disease is very essential. This is helpful not only for managing diabetes but also for the preservation of kidney functions. Good control over blood glucoseThe progression of a kidney disease slows down if there is a good control over blood sugar. Thus, the risk for kidney complications is greatly reduced. This is opposed to the popular belief. Sugar containing foods can be eaten by diabetics. However, they must be a part of a healthy diet which includes vegetables, fruits, healthy fats, proteins and whole grains. One must take note of carbohydrates as well.  The total intake of carbohydrates should be added up. This should have a consistency from meal to meal. This can also help in the prevention of sugar spikes. Instead of choosing refined grains, whole grains should be chosen. Normal blood lipids should be maintainedThe blood lipids of diabetics are often very abnormal. They are characterized by low HDL cholesterol, high LDL cholesterol and increase in triglyceride levels. Modifications should be made in the diet for improving the blood lipids. The Tran’s fats and saturated fats should be limited. Various simple measures should be used to trim the fats. Fat free and lean meats should be chosen.  Fried foods should be substituted with baked foods. Food labels should be checked for cholesterol. Intake of proteins should be modulateThe intake of proteins should be restricted. They help a lot in controlling kidney disease. This is an important part of the diet for diabetics with kidney disease. If blood sugar is controlled well, the need for protein will increase. One must take 15 to 20 percent of calories. This is applicable to various diabetic patients. However, a person should check out with the health care team. Processed foods must be avoidedProcessed foods are often packed with phosphorous and sodium. They prove to be very problematic for diabetic and kidney patients. The risk of hypertension is increased due to high sodium intake. Processed foods should be avoided. The use of table salt should be limited. Thus, a proper diet for diabetics with kidney disease will help in maintaining the levels of blood glucose.Source: Free Articles from ArticlesFactory.com

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The author has given good information in this article about diet for diabetes patients with kidney disease.

Kidney Health: It’s Not Just About Kidney Stones

A kidney is a reddish brown, bean-shaped organ that filterswaste minerals and toxins from the blood. The kidneysregulate acid concentration and the kidneys maintain thewater balance in the human body by producing urine.

Kidneys also make hormones that help keep bones strong bloodhealthy.

Kidneys that aren’t functioning properly allow harmfultoxins to build up. This may causes blood pressure to rise,the body will accumulate fluids, and may not produce enoughred blood cells.

Here are the most common kidney problems.

Kidney Stones: A kidney stone is a hard mass thataccumulates in the urinary tract when crystals separate fromthe urine and build up on the inner surfaces of the kidney.In most people, urine contains chemicals that prevent thesecrystals from forming kidney stones. People who suffer fromkidney stones, for reasons that aren’t always completelyunderstood, don’t have inhibitors that prevent crystalformation.

Anyone who has ever had kidney stones will tell you the paincan be so severe that it reduces them to tears.

Kidney stones are not a product of modern diets orlifestyle. Evidence of kidney stones has been found in 7000year old human remains in Egypt.

Men tend to get kidney stones more often than women.

Kidney Infections: If a person has low resistance, germsfrom the bladder can travel up the ureters to the kidneysand begin to multiply. An acute kidney infection startssuddenly with severe symptoms, then quickly comes to an end.Achronic kidney infection develops slowly and grows worsewith time. A chronic kidney infection can lead to kidneyfailure.

Kidney Cysts: A kidney cyst is an abnormal pouch thatcontains fluid. The simple kidney cyst is the most commonform.

The cause of a simple kidney cyst isn’t completelyunderstood. But there’s no evidence that kidney cysts are aninherited condition. One or more kidney cysts may develop ata time on the small tubes in the kidneys.

Kidney cysts do not generally present symptoms and usuallykidney cysts  cause no harm. Very often people don’t evenknow they have a kidney cyst. However, a kidney cyst cancause pain if it grows large enough to press on otherorgans.

Sometimes a kidney cyst can become infected and start tobleed. If that happens, a kidney cyst can increase bloodpressure, but it usually don’t impair kidney function.

A kidney cyst won’t require treatment if no complicationsare present.  But if symptoms occur, a kidney cyst mayrequire surgery.

Kidney Cancer: Kidney cancer accounts for approximatelythree percent of all adult cancers in the United States. TheAmerican Cancer Society reports that more than 30,000 newcases of kidney cancer are diagnosed each year and about12,000 people die from kidney cancer annually.

Kidney cancer tends to appear in adults in middle age,usually after age 50. Kidney cancer strikes men twice asoften as women.

The most common type of kidney cancer occurs in the part ofthe kidney that filters blood and produces the urine. Thistype of kidney cancer is called renal cell cancerFree Articles, or renalcell carcinoma. Another type of adult kidney cancer is atumor which arises in the part of the kidney where the urinecollects. This type of kidney cancer is called transitionalcell carcinoma. The most frequent sign of kidney cancer inadults is blood in the urine.

Symptoms and treatment for the kidney disorders describedabove can be found at kidneys and kidney stones 

A brief guide to the control and treatment of diabetic kidney disease (DKD)

Diabetic kidney disease (DKD) refers to kidney damage caused by chronic hyperglycemia. Clinically, it is mainly characterized by continuous albuminuria and/or reduced glomerular filtration rate (GFR). According to reports, about 20% to 40% of diabetic patients worldwide have DKD, and the prevalence of DKD is on the rise. What’s worse, the current situation of DKD prevention and control has encountered a bottleneck as the treatment rate of DKD patients is not high: only 50.8% of patients with albuminuria and 49.0% of CKD patients received ACEI/ARB treatment.

 

What are the treatment approaches for DKD?

The cause of DKD is unknown. The current treatment measures are mainly made in an effort to control the risk factors of DKD, which includes poor blood glucose control, poor blood pressure control, hyperlipidemia, hyperuricemia, obesity, smoking, socioeconomic status, and lack of exercise.

According to the 2018 American and European Diabetes Association consensus on T2DM hyperglycemia management, for T2DM patients with CKD, if their blood glucose level is still not normal after administration of metformin and if the eGFR is at an appropriate level, SGLT2 inhibitors may be a good choice. And in cases where SGLT2 inhibitors are intolerant or contraindicated, GLP-1 receptor agonist should be selected.

Antihypertensive drug of choice for DKD patients are angiotensin converting enzyme inhibitors (ACEI) and angiotensin-receptor blockers (ARB).

For non-dialyzed DKD patients, statins are preferred. It is not recommended to start statin therapy in dialysis patients without statins, but dialysis-dependent patients who have started statin therapy can continue to use it unless side effects occur.

DKD patients should reasonably control protein intake, which is about 0.8 g/kg/d, limit salt intake to

Early dawn: new SGLT2 inhibitor of hypoglycemic agent has renal protective effect

 

Many large-scale studies have shown that the new hypoglycemic agent SGLT2 inhibitor has a renal protective effect. Post hoc analysis of the EMPA-REG study showed that compared to placebo, empagliflozin slowed the progression of kidney disease and reduced the risk of renal composite endpoints (doubling serum creatinine, renal replacement therapy, or death from kidney disease) by 46%. The exploratory endpoint of the CANVAS study showed that, compared to placebo, canagliflozin reduced the risk of renal composite endpoints (continuous doubling of creatinine, ESRD, and death from kidney disease) by 47%, and the risk of albuminuria progression by 27%. The DECLARE study presets a secondary endpoint that shows that dapagliflozin reduces the risk of renal endpoints (eGFR reduced by ≥40% and

Potential research: new kidney protective drugs emerge          

It is currently believed that oxidative stress, inflammation and fibrosis contribute to the development of DKD. The development of new renal protective drugs has focused on endothelin-1 receptor antagonists, mineralocorticoid receptor antagonists, antioxidant stress drugs, anti-inflammatory drugs, anti-fibrotic drugs and multi-factor targeted drugs.

Endothelin-1 receptor antagonists produce vasoconstriction, pro-inflammatory and podocyte injury-related effects through ETA receptors, activate ETB receptors, cause vasodilation and activate NO. Phase II clinical trials conducted in DKD patients have shown that the selective endothelin-1 receptor antagonist, atrasentan, can significantly reduce proteinuria while increasing the decrease in urine albumin-creatinine ratio (UACR). Finerenone is a new generation of oral mineralocorticoid receptor antagonists. ARTS-DN results show that finerenone can significantly reduce UACR in a dose-dependent manner. The multi-factor targeted drug Klotho has been shown to have renal protection. Animal studies have shown that over-expressing Klotho can significantly improve renal fibrosis in DKD mice, and inhibit urinary protein levels by inhibiting fibrosis and epithelial-mesenchymal transition. Clinical studies have shown that recombinant human α-Klotho (0.3 mg/kg) can significantly improve renal function and renal fibrosis. Other new drugs such as TGF-β inhibitors, phosphodiesterase inhibitors, and serotonin 2a receptor antagonists are also in clinical research. 

Conclusion

The etiology of DKD is not clear. At present, the main treatment is to control risk factors, but the long-term efficacy is not very satisfactory. In the clinical treatment process, it is necessary to take into account multi-factor common intervention, multi-pronged approach, and comprehensive management. Fortunately, there is increasing evidence of independent renal protective effects of new hypoglycemic agents, which definitely brings good news to DKD patients. HoweverArticle Search, a large number of clinical studies on DKD pathogenesis-related drugs are still needed in order to prove their effectiveness and safety.

Running Itself Has a Lot Benefits

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First of all, running can help you bid farewell to the bloated body. The reason that why many people start running is that weight loss can be reduced through running. In order to lose weight, and running is the best way indeed.Running would like to burn more calories per minute than any other sports.Secondly, running is able to avoid your bones and muscles’ degeneration. With regard to our bones and your body, there have to be a coordinate relationship between each other. Our bones is becoming more and more weaker by sitting in front of the monitor for a long-term. Your bones are likely to be in good health if sports are often done by you. That is to say that our internal body will aging slower by taking this action. Regular high-intensity exercise, such as running, is proved to promote the growth of hormones. Hormone is a kind of continuous medical injection that celebrities use in order to make themselves look younger.Third of all, running can resist diseases. Running can reduce the risk of stroke and breast cancer. As for patients who are likely to cause or have already in the early stage of osteoporosis, diabetes, and hypertension, doctors would like to suggest them to conduct frequently running. Fourth of all, the overall body standard are able to be maintained and improved by running.Running is the best sport that people can take to exercise body. Cholesterol can be enhanced, blood clots risk can be reduced, and fifty percent of your lung that is often in idle condition can be exercised by it. Moreover, in order to boost your immune system, running will boost your lymph cells as well.Fifthly, running will make you more confident. Be the same to other single exercise, jogging can help you own more confidence. Time and time again, your attempts have been finished through running, and it makes you have more power as well as more confidence. It makes it possible for you to across a mountain peak, and traverse certain obstacle as well. You will be given power and sense of freedom when you are conscious that you have a stronger body. Self-confidence is a valuable asset of the runners who have had a successful weight loss and have reached to the ideal body in his mind by running.The sixth point is that you would like to relax yourself and reduce pressure through running. Your troubles are certain to fade away when you are bathing in the beautiful scenery, for jogging has the ability to distract your attention. Long-distance race is suitable for those people who are in a bunch of headaches and worrisome thoughts. A long -distance running for two hours will be the best idea to relieve your nervousness and clear your mind than any other ideas. You can have a nice mood if you run quickly when you feel depressive at this time. Finally, running can be conducted anywhere and it is very simple. Not all the movement can be done anywhere and equipment will be needed in lots of sports. At present, we can begin to run if a good pair of shoes are possessed by us.

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